Objective To test the hypothesis that lorazepam has better efficacy and safety than diazepam for treating pediatric status epilepticus.ĭesign, Setting, and Participants This double-blind, randomized clinical trial was conducted from March 1, 2008, to March 14, 2012. Some studies suggest that lorazepam may be more effective or safer than diazepam, but lorazepam is not Food and Drug Administration approved for this indication. Importance Benzodiazepines are considered first-line therapy for pediatric status epilepticus.
Challenges in Clinical Electrocardiography.
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